Endocrine Abstracts

Objective: to analyze the dietary and metabolic factors predictive of the occurrence of pancreatitis in patients with type 1 diabetes mellitus (T1DM).Patients and Methods: Analytical case-control study of 31 T1DM patients separated into two subgroups: G1 (n=10): T1DM cases with pancreatitis. G2 (n=21): T1DM controls without pancreatitis.Results: The age at diagnosis of T1DM was comparable between the two groups. A...

Objective: To assess the predictive factors for the occurrence of urinary dysfunction (UD) in patients with diabetes mellitus (DM).Patients and Methods: Case-control study comparing two groups of patients suffering from DM: G1 (n=159) with UD vs G2 (n=41) without UD.Results: G1 patients were older than G2 patients (59.7±10.3 vs 58±12 years) with no significant difference in gender. The duration of diabetes w...

Objective: To determine the prevalence and analyze the predictive value of erectile dysfunction (ED) in the occurrence of fictional disorders (MD) in men with diabetes mellitus (DM).Patients and Methods: Cross-sectional study of 90 men presenting with DM. A comparative analysis was performed between two subgroups: G1 (n=75) with MD vs G2 (n=15) without MD.Results: G1 patients were older than G2 (59.7±10.3 vs 58...

Objective: To test the reliability of the classic diabetic survey (DS) in the diagnosis of malnutrition in elderly patients with diabetes mellitus (DM).Patients and Methods: Analytical study of 55 patients aged over 65 years who were hospitalized in the Endocrinology Department. A DS was performed for all patients. The diagnosis of malnutrition was established according to the criteria proposed by the HAS 2021. Two subgroups were compared: G1 (n...

Objective: To determine the influence of metabolic disturbances associated with diabetes mellitus (DM) on the clinical manifestations of the diabetic neurogenic bladder (DNB).Patients and Methods: Analytical cross-sectional study comparing two groups of patients suffering from DM: G1 (n=159) with manifestations of DNB versus G2 (n=41) without signs of DNB.Results: G2 patients were younger than G1 patients (58±1...

Objective: To describe the phenotypic and molecular characteristics of familial thyroid dyshormonogenesis (FTDH) in the Tunisian population.Patients and Methods: A retrospective descriptive study including two related (R and K) with high consanguinity whose members are carriers of FTDH. Biological and genetic screening was proposed for all consenting members.Results: FTDH was identified in 11 patients (8 girls, 3 boys) with a mean ...

Background: Diabetes mellitus poses a global chronic health challenge, with Tunisia experiencing a concerning surge in type 2 diabetes (T2D) prevalence. Cardiovascular and renal complications are prominent and severe consequences associated with T2D. Evaluating the costs related to managing these complications is crucial to enhance care quality, optimize resource utilization, and ultimately reduce the growing economic and social burden of this chronic disease.<p class="abs...

Introduction: The H syndrome, an autosomal recessive genodermatosis, is characterized by cutaneous and systemic manifestations resulting from mutations in the SLC29A3 gene (10q22.2), leading to histiocytic infiltration of multiple organs. This study presents a new observation of H syndrome.Observation: We report the case of a 33-year-old patient, born of consanguineous parents, with a history of diabetes diagnosed at the age of 28 and treated with oral a...

Background: Diabetes mellitus presents a pervasive global health challenge, and Tunisia grapples with a concerning upswing in the prevalence of type 2 diabetes (T2D). Cardiovascular and renal complications stand out as prevalent and severe outcomes linked to T2D. Evaluating the costs associated with managing these complications in T2D patients is pivotal for improving care quality, optimizing resource allocation, and ultimately mitigating the escalating economic and social bur...

Introduction: Metformin, the primary treatment for type 2 diabetes, is renowned for its positive effects on carbohydrate metabolism, weight management, and vascular health. Despite these well-established benefits, prolonged use of metformin has been linked to potential adverse reactions, including a decrease in serum vitamin B12 levels and the development of anemia1. This case further emphasizes the complexities associated with metformin use by introducing an unusua...